Locations
Radiation Oncology UMH
22 South Greene Street
Baltimore,
MD
21201
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Radiation Oncology - MPTC
850 West Baltimore Street
Baltimore,
MD
21201
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About Me
Dr. Tran treats patients with cancers of the genitourinary system and uses stereotactic radiation techniques (such as SRS and SBRT/SABR) for the treatment of patients with cancer that oligometastatic disease, which is cancer that has spread but in a limited way.
Dr. Tran is professor and vice-chair for research of radiation oncology at the University of Maryland School of Medicine.
Dr. Tran has published more than 175 scholarly works in peer-reviewed journals, has received numerous awards for his research, and is a primary investigator on a number of clinical trials.
He is a member and held leadership positions in the Radiological Society of North America (RSNA), NRG Oncology and the American Society for Radiology Oncology (ASTRO), and is board-certified in radiation oncology by the American Board of Radiology. He is also a senior editor/editorial board member of Cancer Research and the Journal of Clinical Oncology.
Dr. Tran completed his medical and graduate training at the Oregon Health & Sciences University in Portland. He conducted a residency in radiation oncology at the Stanford University Medical Center and spent the last decade on the staff of Johns Hopkins reaching the level of tenured professor before joining the University of Maryland.
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Research Summary
Dr. Tran’s research focuses on the improvement of clinical radiotherapy for the treatment of prostate, as well as adrenal, bladder, penile, testicular and urethral cancer.
To learn how tumors arise, how they spread and why some cancers are resistant to treatment, he studies tumor cell epithelial plasticity - transitions of epithelial and mesenchymal cellular states.
Dr. Tran and his laboratory focus their studies on tumor cell epithelial plasticity - the transitions between epithelial and mesenchymal cellular states and the implications of these transitions for tumorigenesis, cancer treatment resistance and radiation-induced fibrosis. Their research utilizes a variety of inducible transgenic mouse models, non-invasive rodent imaging as well as more traditional molecular, biochemical and cell biologic approaches. One of these transitions, known as epithelial-mesenchymal transition (EMT), is a conserved developmental program that when inappropriately activated in post-natal life has been associated with organ fibrosis, tumorigenesis and metastasis.
A major focus of the laboratory is the use of inducible mouse models to simulate molecularly targeted therapies for malignancies and radiation-induced late effects.
Another focus of the laboratory is the study of novel targeted agents as tumor-selective radiosensitizers to increase the therapeutic ratio of clinical radiotherapy.
The Tran lab is committed to translating discoveries from the laboratory bench into novel cancer prevention, diagnostic and treatment approaches that can be tested in the clinic. Please visit https://www.tranlaboratory.com/
